Showing posts with label DNA. Show all posts
Showing posts with label DNA. Show all posts

Saturday, 25 November 2006

Race Is

Pot is bad for you, and good for you. In doses smaller than a joint, it's bad; in large doses good- but all pot degrades into smaller doses. They're working on the first quantum computers. We may be able to make hearts from one stem cell from a baby. Molecules provide an anchor for memories. Black holes spin really fast. And the article for today's musings: race seems to be based on DNA .

Geneticists have found that humans can vary as much as 12% in their genetic code, putting paid to the notion that we are 99.9% identical. That idea of mass similarity seems to have no scientific merit, as attractive as it is. About 12% of our DNA varies in the number of copies it has- and this tends to correspond with the ethnic group self-identification of individuals. Basically there are genetic differences between those of European, African, and Asian descent. And this isn't a crack-pot study- it's the third study recently to indicate massive differences by race.

How does this work, considering recent studies have indicated that we are 97% the same as chimpanzees and 99.5% the same as Neanderthals? How then can we as humans be 12% different? As I understand it, our DNA between one human and another is still much more similar than between us and another species or subspecies. We still have a much smaller genetic diversity than most species, indicating perhaps a historical bottleneck. However, up to 12% of our DNA varies- and this corresponds to traditional racial classifications. It's been long known that there are differences in certain points, such as the African-American heightened tendency towards sickle-cell anemia. But this is the first study to quantify the difference to such a great degree.

What it doesn't indicate: that one group is superior to another, or that genetics are the big deal. As the study mentions, wolves and dogs are almost completely genetically the same, but they act and look far different. Culture and gene expression both play a role in differences.

And yet, this should come as no suprise. It is standard evolutionary fare: a population breeding separately with another population will start to build up genetic differences. Indeed, this is how we are able to determine that the Austrailian Aboriginals isolated themselves from the rest of the species long ago, 30,000 years ago- the oldest isolation split we know of. The longer a group is isolated, the more different one would expect the genes to be, leading eventually to a speciation event.

Perhaps there's something here to celebrate. And to learn. We are different, yet equal. It's hard to grasp. But it's what we find in the Garden. Eve is created as a help-meet, equal to Adam. And yet she is far, far different. God calls the most different, male and female, to learn to love each other. Love is not easy, and it's not supposed to be. It's harder especially to love those that are different. It's far easier to love myself, or at the very least, my clone. I think that's a big reason why God calls us to love a woman- to learn to love the different.

And now we see how this opportunity is present in groups of people as well. Not only are they different culturally, but also biologically. Yet just like men and women, no group is inferior or should be subservient to another. We are suddenly impressed with the huge realization that "those other people" are really different. And equal to me, both spiritually and hopefully in the world of human affairs. It's no longer a matter of my group being better, or pretending that we are all the same in a giant melting pot. I now have to learn what true love is- loving the different. I now have the opportunity to struggle through that to reach true love.

Perhaps one day there will be discovered that there are certain genetic tendencies that make one group better than another in certain areas- stronger legs or some such. But probably at that point we will have reached the future state that everyone is predicting- through interbreeding we are all dark-skinned, with those recessive traits of blond hair and blue eyes nearly bred out of existence. It's through the process of loving the different that I discover my basic similarity to them.

Saturday, 18 November 2006

Who's Your Daddy?

Today's World Science revelations included Spider Monkeys having developed a natural perfume based on leaves (naturally used most often by the males); dark energy has been around for a long time and is causing the universe to expand at an increasingly fast rate; red wine is good; and new subatomic particles. I'll be focusing on the sequencing of Neanderthal DNA.

This is pretty cool stuff. Based on a Neanderthal thigh bone they have found a genetic similarity between us and them of 99.5%, although in many places they are more similar to chimpanzees than us. (By comparison humans and chimpanzees differ by 96%, and rats from mice by ten times that amount.) The DNA shows that the last time we had a common ancestor was 706,000 years ago, and that our DNA hasn't mixed for the last 330,000 years. (The last time chimps and us had a common ancestor was 6 million years ago.)

We, Homo sapiens, arrived in Europe between 40,000-50,000 years ago. Neanderthals disappeared completely between 33,000-24,000 years ago. And ever since then scientists have wondered why.

There's been two primary hypothesis. Firstly that we killed them off. This makes us somehow better adapted to the climate. We didn't necessarily have to kill them off through warfare- it could have been that we simply outcompeted them for space and food, though some studies indicate signs of violence on Neanderthal bones. Perhaps the change in climate at the time was one that Neanderthals were pre-conditioned to not be as adaptive to, but our Cro-Magnon ancestors were. If this is the case, then they are a separate species at the end, with no mixing between us, and should be called Homo neanderthalis.

The other option is that they disappeared through sex. Or rather, that they are still with us. We interbred with them to such an extent that their genes merged with us, and traces of Neanderthals still remain in modern humans. In which case they would be a subspecies, and properly called Homo sapiens neanderthalis. Of course, this wouldn't exclude the possibility of Homo sapiens sapiens (us) killing off large portions of them as well. And in either scenario, we once were of the same stock- the species concept is somewhat arbitrary, as it is always in a state of evolving flux. We can only say that if an animal can't, or doesn't, interbreed with another animal, it is of a different species. (Higher taxa are determined in a far more general manner, losing even this minimal definitiveness.)

This study indicates that the killing option was more likely. If the last time our genes were the same was 330,000 years ago, this was a long time after we diverged as modern humans, 130,000 years ago. Therefore we weren't around to interbreed with the Neanderthals at the time our DNA indicates similarities. However, other recent studies of the DNA of the very same bones indicate great similarites between the two lines, indicating continued sexual activity between the two groups.

The data is therefore still indeterminative at this point. However, the earlier study indicating sex between the two parties used a method that some say results in incomplete results mixed with intrusive DNA. This same analysis suggests that the difference between human and Neanderthal DNA will show to be less than that between the highly diverse African human populations. I'm personally rooting for the sex option, and I still have hope that it becomes the final conclusion. Probably a big part of this is my natural liberal bias- "Make love, not war" and all. Just a much more romantic notion to think that they disappeared that way, rather than us committing, however inadvertedly, the first and greatest mass genocide of our species. It doesn't help that the ones possibly committing this were my European ancestors.

But there are other reasons to hope for this. We know that Neanderthals had tools, cared for their injured, made art, abstract thinking, and probably buried their dead. This means something pretty far advanced. And however one determines the presence of the soul, life after death seems to be a big part of that, as it indicates the presence of a belief in the afterlife, and therefore some sort of religious belief.

Even more so, Neanderthal brain cases were larger than our own. They were also larger in body, and their brains were structured differently than ours- but there is the possibility that they were actually smarter. Solid evidence indeed that a bigger brain is not necessarily a selective advantage. I'd hate to lose out on all of that brain, culture, and heritage, wasted away, without a memory or a presence. Better to hope, however indefinite the evidence is at the moment, that there is a bit of Neanderthal in me, and you. Better to take the opportunity to glory in the compliment of intelligence, the next time somebody calls you a Neanderthal.
This is the discussion of the World Science updates as they become available.
Your thoughts are most welcome here.